Package: HLAtools 1.18.0
HLAtools: Toolkit for HLA Immunogenomics
A toolkit for the analysis and management of data for genes in the so-called "Human Leukocyte Antigen" (HLA) region. Functions extract reference data from the Anthony Nolan HLA Informatics Group/ImmunoGeneTics HLA 'GitHub' repository (ANHIG/IMGTHLA) <https://github.com/ANHIG/IMGTHLA>, validate Genotype List (GL) Strings, convert between UNIFORMAT and GL String Code (GLSC) formats, translate HLA alleles and GLSCs across ImmunoPolymorphism Database (IPD) IMGT/HLA Database release versions, identify differences between pairs of alleles at a locus, generate customized, multi-position sequence alignments, trim and convert allele-names across nomenclature epochs, and extend existing data-analysis methods. Tran et al., (2025) <doi:10.1111/iji.70013>.
Authors:
HLAtools_1.18.0.tar.gz
HLAtools_1.18.0.zip(r-4.7-any)HLAtools_1.18.0.zip(r-4.6-any)HLAtools_1.18.0.zip(r-4.5-any)
HLAtools_1.18.0.tgz(r-4.6-any)HLAtools_1.18.0.tgz(r-4.5-any)
HLAtools_1.18.0.tar.gz(r-4.7-any)HLAtools_1.18.0.tar.gz(r-4.6-any)
HLAtools_1.18.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
HLAtools/json (API)
| # Install 'HLAtools' in R: |
| install.packages('HLAtools', repos = c('https://sjmack.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/sjmack/hlatools/issues
- alleleListHistory - Allele Names Across All Release Versions
- alleleStatus - Key data for each allele in the IPD-IMGT/HLA Database. A list object consisting of two elements - $AlleleStatus and $version. This object is built by the updateAlleleStatus() function.
- fragmentFeatureNames - Gene Features of HLA Pseudogenes and Gene Fragments
- GLSC.ex - Example Data Frame of Genotype List String Code Data
- GLstring.ex - Example Data Frame of Genotype List String Data.
- HLAatlas - Boundary Positions of Exons, Introns and UTRs in Amino Acid, cDNA and gDNA Alignments
- HLAgazetteer - Functional and Organizational Categories of Genes Supported by the IPD-IMGT/HLA Database
- IMGTGenomicReferences - Genomic Reference Alleles for each Gene in the IPD-IMGT/HLA Database
- IMGTHLAGeneTypes - Molecular characteristics of the Genes Curated by the IPD-IMGT/HLA Database
- sHLAdata - Synthetic HLA Data for use with Package Examples
- UNIFORMAT.example - Example Data Frame of UNIFORMAT Data.
- WMDASerologicalRelationships - Descriptions of relationships between serologically defined HLA antigens and HLA alleles. rel_ser_ser describes relationships between all defined antigens, broad antigens, split antigens and associated antigens. rel_dna_ser describes the known unambiguous, possible or seorlogically equivalent antigen for each HLA allele.
Last updated from:2be9b94c57. Checks:9 OK. Indexed: yes.
| Target | Result | Time | Files | Syslog |
|---|---|---|---|---|
| linux-devel | OK | 219 | ||
| source / vignettes | OK | 273 | ||
| linux-release | OK | 217 | ||
| macos-release | OK | 151 | ||
| macos-oldrel | OK | 179 | ||
| windows-devel | OK | 146 | ||
| windows-release | OK | 130 | ||
| windows-oldrel | OK | 130 | ||
| wasm-release | OK | 129 |
Exports:addCodonLinealignmentFullalignmentSearchalleleStatusLookupalleleStatusSummaryalleleTrimappendWMDAatlasFullatlasMakerBDstratBDtoPyPopbuildAlignmentsbuildGazetteerbuildGenomicReferencesbuildIMGTHLAGeneTypesbuildWMDASerRelcheckAlignTypecheckgDNAstartcheckSourcecheckVersioncompareSequencesconvertAnycountSpacescustomAlignexpandAntigenTermsexpandVersionffNflattenTableformatHeadgenomicReferencesLookupgetAlignmentNamesgetFieldgetLatestVersionGIANTGLStoUNIGLtoUNGLupdateGLVGLV2GLvalidateGLVhelpermotifMatchmultiAlignmultiAlleleTrimmultiGLStoUNImultiLocusValidationmultiQueryAlleleStatusmultiQueryReleasemultiSearchmultiTranslateGLstringmultiUNItoGLSmultiUpdateGLnumFieldsparseAlignmentHeadposSortpypopHeadersqueryAlleleStatusqueryPositionsqueryRelDNASerqueryReleaseredecrelDNASerLookuprelRiskrelSerSerLookuprepoVersionsquashVersiontranslateAlleletranslateGLstringtypeToSourceuniAlignuniSearchUNItoGLSUNtoGLupdateAllupdateAlleleListHistoryupdateAlleleStatusupdateGLvalidateAllelevalidateGLstringvalidateLocusvalidateMotifvalidatePositionsvalidateUniformatvalidateVersionvalidationByTranslationvariantTableverifyAllele
Dependencies:askpassbitbit64bootcellrangerclassclicliprcpp11crayoncurldata.tableDescToolsdplyre1071ExactexpmfmsbforcatsfsgenericsgldgluehavenhmshttrjsonlitelatticelifecyclelmommagrittrMASSMatrixmimemvtnormopensslpillarpkgconfigprettyunitsprogressproxyR6RcppreadrreadxlrematchrlangrootSolverstudioapirvestselectrstringistringrsystibbletidyselecttzdbutf8vctrsvroomwithrxfunxml2
